Combining disciplines: DeDNAed combines physics and biology to develop new biosensors
The presentation of the results of the European initiative DeDNAed, in which TECNALIA is participating, will take place on 17 July. One of the speakers will be Verónica Mora, Health Researcher at TECNALIA and biomaterials expert.
New generation of biosensors
This project, in which TECNALIA is participating, combines the advantages of surface-enhanced Raman spectroscopy (SERS) and DNA origami to develop a new generation of biosensors.
- The DeDNAed project aims to develop an innovative and advanced biosensor platform: it stands out for its sensitivity, versatility and ultra-fast speed through an optical approach.
- The platform will be based on the combination and integration of sensor elements (transducer and bioreceptor) via DNA origami.
- DNA origami is used to control the position of these elements and, therefore, the architecture of the sensor on a nanometric scale.
Objectives and benefits of this initiative
The biorecognition element (antibody or aptamer) will have atomic nanoclusters integrated into its structure. Transduction will be achieved through changes in the SERS signal when the analyte binds to the bioreceptor. An improvement to the SERS signal will be achieved by the inclusion of nanoparticles (NPs) in strategic locations.
This approach will offer significant advantages such as increased sensitivity, rapid response and suitability for point-of-care (PoC) diagnostics.
Join this webinar and discover all the details and key results, as told by eight leading expert speakers.
This project has received funding from the Horizon 2020 EU research and innovation program, with Subsidy Agreement number 964248.